What Are Antidepressants, and How Do They Work?

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From a very scientific stand point, an antidepressant is inanimate models we have these models of what's called learn helpless, so if in this case a rat for example is under stress and eventually it starts to give up. And we give them a compound and he starts fighting again, then and this is how antidepressants were discovered they maybe limited to that person's potential.

So that is from a pure, that's how these compounds come to the market. From a clinical standpoint an antidepressant is any treatment that essentially reduces and reverses depression and by depression I mean the sustained periods of [INAUDIBLE] and then depression occurs with much huge pressure/g.

But the brief answer one would thinking that we honestly understand how the brain works and then went ahead and made a diagnostic. But that's not how it works, it works in reverse. We found compounds that get people better and then we try to understand how they work and over the last 50 years or so we believe that increases neurochemicals in the brain and the biggest ones are seratonin, neuro-epinephrin and dopamine.

So we believe and see that increase of those neurochemicals that have altered the person's potential. Now we are beginning to find out that the picture is a lot more complicated, there is a lot that happens downstream of those neurochemicals, where new cells may form, or new connections are formed and even that, in specific parts of the brain.

Two areas that I guess was going to over time, one area is important for motivation and enjoyment and another area important for how we link our experiences, previous experiences how we react to those ones..