Can Depression Affect a Person's Sex Drive?

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Absolutely. When we're depressed one of the hallmarks is called anhedonia, where you fail to enjoy things and if you're failing to enjoy things sex can feel like going through the motions. It can feel even disappointing whereas it used to feel good. You can end up feeling so withdrawn, you don't feel present with your partner and that leads to crummy sex, and it decreases your drive.

There's also an interaction in the brain between the neurochemicals that drive mood and also drive libido. So very often they go together, plus if you're taking an antidepressant it can also suppress your libido, your sex drive.