When did personalized treatment begin in the field of oncology?
In this video, learn how breast cancer was the first opportunity for the birth of personalized medicine, according to David Daly, Head of Oncology, Life Technologies. Watch this HealthMakers video to learn more about personalized treatment.
Transcript
Breast cancer was really where the first breakthrough took place, with characterization of the HER2 gene and its expression,
alongside the development of Herceptin therapy. [MUSIC PLAYING]
Women today who express HER2 receive Herceptin therapy. While not all of them benefit--
about 30% of women who express HER2 benefit-- the benefits are extremely positive.
So yes, really understanding the genetic component.
HER2 also expresses in gastric cancers. So utilizing those same HER2 inhibitors that are today used in breast cancer now being
used in gastric cancers. We're identifying HER2 expression in lung tumors. So how do lung tumors respond to these anti-HER2 therapies
is another area of experiment. So we're finding that pathways that are activated in solid tumors transcend the location
or the site of the tumor. No longer is it necessary to have a site of origin, per se.
It's characterizing the pathway and the different components related to that tumor that are more important.
cancer
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