How Are Genetics Impacting the Future of Cancer Research?

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We're doing other new things with cancers in and around the eye of a moral soul catering. Most of them are stimulated by the events and genomec medicine and genetics and in technology. And we've been able to do more in the last five years than I did in the previous 25 years, and I think the pace will only continue again it's because of the events in genetics and technology.

We are closer and close to understanding why cancer cells become cancer cells and why cancer cells are resistive to treatment translating that into more effective treatments has been difficult. However, probably most cancer originates by only limited numbers of pathways I think of this as coming into New York city.

There are a limited number of ways you can get into Manhattan, but once you are in Manhattan you can do all kinds of different things. Well, it appears that to develop cancer you need one of this pathways, and they are limited we really don't know how many of this pathways they are, it's more than a handful but's fewer than 20.

So, it probably is that the way to go about to go about this genetically is to stop them at the George Washington bridge, not when they get down to 42nd street. That means that the treatments for very different cancers maybe the same, and the treatments for the exact same cancer maybe very different.

Because the cancer cells are like the people coming into Manhattan, they're very different once they get off the George Washington Bridge they've gone to different places, they've experienced different things, they've changed in different ways. Trying to treat them that is difficult because they're so individual, but if you can get them before they get to the George Washington Bridge, you maybe successful, and that's really what targeted molecules are all about.

I'm fortunate because I am in an academic intellectual candy land evermore where catering with these are being monthly, and it's a very exciting time.