What Are the Challenges to Growing Human Cells Outside the Body?

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If you think back to just 30 years ago most primary human cells, most cells from the human body could not be grown outside the body, and just in the last 30 years we have made major advances and now growing most cell types in the body, but it's interesting even now, even now, today, 30 years later there are still certain cell types that we can not grow outside the body, like pancreatic cells, cells from the pancreas or cells from the nerve.

So, even with all the scientific advances we have there are still challenges that still need to be addressed.