Exploring New Treatments for Multiple Sclerosis

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I think if you find the cause of MS then I think you can go for a cure, without it you can't. That's a completely different subject. We are getting very close to the cause of MS, and if we can get there, then I think the cure questions can really be answered realistic way. The brains spinal cord has electrical systems or nerves, and just like the household wire it has a copper wire in the middle that has insulation material, the nerves have axons and myelin and myelin is the covering and MS is an auto immune disease, which is thought to be an auto immune disease, in which the immune system attacks the covering of these nerves called myelin, and then if its unchecked can involve the copper wires themselves the axons.

You either can see the patient every three to six months and pat them on their backs or you can do something about it. Looking into this was to see other types of treatment could remyelinate or regenerate the brain and spinal cord using the patients own stem cells, and then there was this idea that maybe we could harvest patient cells. So, it was kind of more of an evolution rather than an aha moment. There are a MS centers that are legitimately doing it with approval of the FDA equivalent bodies.

And we are the only ones who are doing neural stem cells than anyone in the world that I know of, which are being injected into the spinal fluids. So nobody is doing exactly what we're doing. In our case we started working with bone marrow derived mesenchymal stem cells and we were trying to see if we could coerce them into becoming brain stem cells and neural stem cells, and once we did that in vitro, in petridation the laboratory, we then said why don't we try these studies in mice and go all the way, and we purposely treated this mice after they had become disabled and then found that they were recovering so then that led us to propose these studies to the FDA to try it in humans.

I see us at the point of the first cellphone being invented and that model now wouldn't even be in the shops. So, I think it's like the first thing you do of anything you learn and then you move on. What I hope in the next five years is that this stem cell trial is safe, it's tolerated well and starts giving us the insight into how to get repair started in MS and in other neurological diseases.

If that can be accomplished, I will be ecstatic. There are so many challenges ahead, try to do the best for your patients and everything else will take care of its self, and I certainly am not a role model there many better physicians than myself, but those are the goals that have been driving me. It takes money, it takes patience, it takes endurance, and it takes prayer and belief and purpose of your life and if its in your destiny then I think it will happen. Sometimes you just have to keep asking for divine intervention which I do.