What are the side effects of phytonadione?

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A serious, but rare, effect of phytonadione (vitamin K) is anaphylaxis. This is a severe allergic response to phytonadione in which your body's immune system treats the vitamin K as a harmful, rather than helpful, substance. This causes the release of many chemicals that can damage organs throughout your body. Low blood pressure, difficulty breathing, or even a total stop in breathing are all indications that you are having an anaphylactic reaction to phytonadione.