What are side effects of folic acid supplements?

Although folic acid is basically nontoxic in humans, some side effects have been reported. Allergic reactions may occur, so, call the doctor immediately if these symptoms are seen:
  • Difficulty breathing
  • Swelling around the mouth and throat
  • Skin rash
  • Itching and redness
Nervous system symptoms that have been reported with large daily doses include: irritability, anxiety, sleep problems and depression. Gastrointestinal side effects that have been reported after large daily doses include: nausea, loss of appetite, bloating and gas, bitter, unpleasant taste.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.