What are the risks of taking too much vitamin B6?

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Dariush Mozaffarian, MD
Internal Medicine
Taking too much vitamin B6 on a routine basis can lead to neuropathy, nerve damage that can cause pain, weakness, and loss of sensation. Decades ago, some experts recommended megadoses (roughly 50 to 150 times the recommended dose) of vitamin B6 to treat carpal tunnel syndrome -- a pinched nerve in the wrist that can cause finger tingling and numbness. But several cases of people developing neuropathy as a result of this treatment have been reported in the medical literature. Vitamin B6 has also been touted as a treatment for premenstrual syndrome, but there's no evidence it helps -- and a review article reported neuropathy symptoms in 23 of 58 women taking daily vitamin B6 for this reason.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.