What are precautions for cyanocobalamin (Vitamin B12)?

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There are several precautions you should be aware of before you begin taking cyanocobalamin (vitamin B12) injection, nasal gel (Nascobal) or tablets. These include:

  • Talk to your doctor if you think you are allergic to cyanocobalamin, any other vitamins or cobalt.
  • Make sure you tell your doctor and pharmacist every nonprescription substance you are taking, including vitamins, aspirin or any dietary supplements, including any prescription drugs you are taking.
  • Make sure you tell your doctor if you are taking the following drugs that may interact: antibiotics such as chloramphenicol, colchicine, folic acid (folate), methotrexate (Rheumatrex, Trexall), para-aminosalicylic acid (Paser) or pyrimethamine (Daraprim).
  • Make sure you tell your doctor if you drink alcohol, if you have had Leber's hereditary optic neuropathy or kidney problems.
  • Make sure you tell your doctor about your plans to get pregnant, if you are currently pregnant or if you are breastfeeding. Cyanocobalamin might cause harm to a developing baby.