How is post-polio syndrome (PPS) treated?


There are currently no effective pharmaceutical or specific treatments for post-polio syndrome (PPS). However, a number of controlled studies have demonstrated that nonfatiguing exercises can improve muscle strength.

In an effort to reduce fatigue, increase strength, and improve quality of life in PPS patients, scientists conducted two controlled studies using low doses of the drug pyridostigmine (Mestinon). These studies showed that pyridostigmine is not helpful for PPS patients.

In another controlled study, scientists concluded that the drug amantadine is not helpful in reducing fatigue. Moreover, other researchers recently evaluated the effectiveness of modafinil (provigil) in reducing fatigue and found no benefit.

Preliminary studies indicate that intravenous immunoglobulin may reduce pain, increase quality of life, and improve strength. Research on the use immunoglobin is ongoing.

The future of PPS treatment may center on nerve growth factors. Since PPS may result from the degeneration of nerve sprouts, growth factors can target these sprouts and help in regenerating new ones.

This answer is based on source information from National Institute of Neurological Disorders and Stroke.

Continue Learning about Viral Infections

Viral Infections

Viral Infections

Viral infections like herpes simplex, respiratory syncytial virus (RSV), chicken pox and rotavirus are infections caused by a virus instead of a bacterium. Viral infections do not respond to antibiotics, but some specific viruses ...

like influenza A and B can be treated with certain antiviral medications. Most commonly, treatment for viral infections includes drinking lots of fluids, getting rest, eating well and letting the illness run its course.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.