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How are high blood pressure and renal artery disease linked?

The kidneys regulate blood pressure by secreting hormones that can increase blood pressure. Narrowing of the kidney arteries (renal artery disease) can restrict blood flow to the kidneys. In response, the kidneys may secrete more hormones to raise blood pressure in hopes of improving kidney blood flow. In this manner, renal artery disease can promote high blood pressure. Paradoxically, high blood pressure can contribute to the formation of the atherosclerotic plaque, which typically causes renal artery disease. 

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