Should I ask my pharmacist about combining medicines and valerian?

If you take valerian, tell your pharmacist about your other medications and/or supplements, especially if they are central nervous system depressants. These include prescription medications for anxiety, sleep and depression, as well as over-the-counter cough syrups, allergy medicines, nighttime pain relievers and certain dietary supplements. It's important to let your pharmacist know about all the drugs and supplements you take so he or she can tell you if any of these interact with valerian.