What should I know about diphtheria CRM197 protein conjugate?

Before you receive the diphtheria CRM197 protein conjugate vaccine, you need to be aware of what to look for in side effects, drug interactions, and possible complications, and when to contact your doctor for help. There may be risks associated with having this vaccine during pregnancy. Studies on animals have shown adverse effects on the fetus in all trimesters. However, there have not been adequate studies in pregnant women that have received the diphtheria CRM197 protein conjugate vaccine. It is always important you tell your doctor if you are pregnant, planning to become pregnant, or breast-feeding.

It is important to tell your doctor if you have Guillain-Barre syndrome, as this vaccine may cause symptoms of that syndrome to return. Also, any disease, such as HIV or cancer, that creates a weakened immune system may cause the vaccine to be much less effective. It is also important to note to your doctor if you have a family history of blood clotting problems.

It is recommended that children between the ages of two months and five years receive this vaccine; but it can also be used in adults that have certain medical conditions. Adequate testing of children less than two months old has not been done.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.