Are there medications to treat uterine fibroids?

Yes. There are a number of medicines used to treat uterine fibroids. The most common medications are non-steroidal anti-inflammatory medicines (NSAIDs) and oral contraceptive pills (OCPs). An example of an NSAID is ibuprofen which is being replaced more commonly by a different NSAID tranexamic acid. This medicine has a direct effect on the lining of the uterus and has shown to help reduce the heavy bleeding that fibroids can cause. Gonadotropin-releasing hormone agonist (ex. Leuprolide or Lupron) is also used but can only be given for a maximum of 6 months due to issues of bone loss. More recently, three additional types of medicines are being studied: progesterone receptor antagonists (ex. mifepristone), specific progesterone receptor modulators (ex. asoprisnil), and aromatase inhibitors (exs. letrozole, anastrozole). The first 2 of these medicines have had concerns for causing endometrial hyperplasia (thickening of the uterine lining) and the third has concerns for bone loss. In addition, using aromatase inhibitors currently to treat bleeding due to fibroids is not a FDA indicted use (aka off-label use) of this drug. 
Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
A fibroid’s location is one of many factors affecting treatment options; among these, medications are sometimes used. Watch the video to learn more about treatment of fibroids.

Continue Learning about Uterine Fibroids Treatment

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.