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What is sodium thiosulfate?

Sodium thiosulfate is administered intravenously (IV) as an antidote for cyanide poisoning. It is also used topically as a lotion to treat a fungal infection. Sodium thiosulfate promotes enzymes that detoxify the cyanide. People also sometimes may be injected with sodium thiosulfate to reduce side effects that they experience from taking cisplatin as a cancer treatment. Sodium thiosulfate lotion is a topical cream in which the drug is paired with salicylic acid and used on the skin to heal a condition called tinea versicolor. The lotion penetrates the skin and eliminates the fungus that produces tinea versicolor. Its brand name is Versiclear lotion.

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