How does mesna treat bladder problems from chemotherapy?

Mesna is a uroprotectant medication. Chemotherapy drugs are normally removed from the bloodstream by the kidneys and broken down into other compounds. These compounds can damage the lining of the bladder and cause blood in the urine, a condition known as hemorrhagic cystitis. Mesna works by binding to these compounds, making them less toxic. They are then excreted from the body in the urine.

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