How does Doryx interact with other medications or foods?

Interactions between Doryx and prescription or over-the-counter medications can limit the potency of Doryx, decrease the effectiveness of other drugs, or increase the side effects of other drugs.

Medications that may limit the potency of Doryx include: products that contain aluminum, magnesium, calcium, or iron (such as antacids, vitamins, supplements, and laxatives); bismuth subsalicylate (for gastrointestinal conditions); barbiturates (for anxiety, surgical anesthesia, and seizures); bile acid sequestrants (for high cholesterol); anti-seizure drugs; sucralfate (for ulcers); and quinapril (for high blood pressure).

Doryx may limit the effectiveness of birth control pills, the oral typhoid vaccine, the BCG vaccine (which prevents tuberculosis), and penicillin antibiotics.

The side effects of the following medications may be increased when taken in combination with Doryx:;; warfarin (for preventing blood clots); retinoids (for skin conditions), and neuromuscular blocking agents (for the prevention of movement during surgery). In addition, the combination of methoxyflurane (an inhaled medication that treats pain during surgical procedures) and Doryx can cause a fatal kidney condition.

Herbal medications can also interact with Doryx. St. John’s wort, a medication used to treat depression, may decrease the potency of Doryx. Both St. John’s wort and dong quai (which is used for a variety of conditions ranging from menopause to heart disease) can exacerbate the sun sensitivity associated with Doryx.

While Doryx levels in the body may be slightly decreased when taken with food, the clinical significance of this is not known. However, this drug may decrease the body’s absorption of calcium, iron, magnesium, zinc, and amino acids in foods. Mixing this medication with applesauce may slightly increase the rate of absorption. Drinking alcohol on a regular basis may make Doryx less effective.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.