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What causes stage 4 squamous cell carcinoma?

Stage 4 squamous cell carcinoma begins in the squamous cells, or keratinocytes, which make up the outer layer of skin. Normally, these cells go through a growth cycle in which old cells die and are pushed out by new cells continuously. In stage 4 squamous cell carcinoma, the DNA that controls that growth cycle is damaged, most commonly by ultraviolet (UV) radiation from the sun. This causes an overgrowth and buildup of squamous cells, which forms a squamous cell carcinoma. If an earlier stage of squamous cell carcinoma is left untreated, it will advance to stage 4, meaning the tumor will grow larger and will spread throughout the body.

Continue Learning about Stage 4 Squamous Cell Carcinoma

How does stage 4 squamous cell carcinoma affect the body?
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Stage 4 squamous cell carcinoma begins in the squamous cells, or keratinocytes, that make up your to...
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What increases my risk for stage 4 squamous cell carcinoma?
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The most significant risk factor for stage 4 squamous cell carcinoma is leaving earlier stages of sq...
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Does sun exposure increase my risk for stage 4 squamous cell carcinoma?
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Sun exposure is one of the most significant risk factors for stage 4 squamous cell carcinoma. Sun ex...
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How do medications treat stage 4 squamous cell carcinoma?
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If medications are used to treat stage 4 squamous cell carcinoma, it's usually in addition to other ...
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.