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Should I tell my pharmacist if I am taking medications and St. John’s wort?

St. John's wort can interact with a wide variety of medications, so have a conversation with your doctor and pharmacist about any other medications you are taking. Be sure to mention if you are currently taking birth control pills, prescription antidepressants, heart medications such as digoxin, anticoagulants like warfarin, HIV medications such as protease inhibitors or seizure medications such as phenytoin or phenobarbital. Taking St. John's wort while you are also taking a prescription antidepressant may increase your risk of a condition called serotonin syndrome, which can be very serious. 

Continue Learning about St. John's Wort

Is St. John’s wort regulated by the FDA?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
St. John's wort is classified by the U.S. Food and Drug Administration (FDA) as a dietary supple...
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How should I store St. John's Wort?
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Store St. John's Wort at room temperature. Keep the product in a container that is shut from he...
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What are the traditional uses of St. John's wort?
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St. John's wort has several traditional uses.Greek and Roman medical sources report the use of St....
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How does St. John's Wort work?
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The active ingredient in St. Johns Wort, hypericin, appears to affect various neurotransmitters, in...
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.