Yes. The two most common types of antidepressants used to treat social anxiety disorders are selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs). Both of these classes of drugs can have side effects such as loss of libido, delayed orgasm, nausea, weight changes, and other problems. Your doctor will try to help minimize these side effects by starting you on a low dose and slowly building up to a therapeutic dose. Be sure to let your doctor know if the side effects of a particular drug are bothersome, because you might get better results with a different antidepressant.