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What is Kleine-Levin syndrome (KLS)?

Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those suffering from KLS are male). KLS is characterized by recurring, but reversible, periods of excessive sleep (up to 20 hours per day). Symptoms occur as "episodes," typically lasting a few days to a few weeks. Episode onset is often abrupt, and may be associated with flu-like symptoms. Excessive food intake, irritability, childishness, disorientation, hallucinations, and an abnormally uninhibited sex drive may be observed during the episodes. Depression can be a consequence, but not a cause, of the disorder. Affected individuals are completely normal between episodes, however they may not be able to recall everything that happened during the episode. It may be weeks or more before symptoms reappear. Symptoms may be related to malfunction of the hypothalamus and thalamus, parts of the brain that govern appetite and sleep.
This answer is based on source information from the National Institute of Neurological Disorders and Stroke .

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.