Is there a connection between sleep apnea and high levels of AST and ALT?

Steven C. Smart, MD
Cardiology (Cardiovascular Disease)
High levels of AST (aspartate aminotransferase) and ALT (alanine aminotransferase), two different types of enzymes in the body, can be signs of muscle injury or, more commonly, liver disease. Indirectly, these may be elevated in sleep apnea patients who have severe heart failure and severely elevated pressure in their lungs. It is often a sign of advanced disease. Most sleep apnea patients demonstrate no elevation in these markers.

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