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Pus-filled sores that break open and crust are usually caused by bacteria that get inside pores. As the bacteria grow into pus-filled pimples, the pimples eventually can break open, bleed, and crust over as the skin heals. Folliculitis and impetigo are causes of pus-filled sores. Herpes simplex virus (oral and genital herpes) and herpes zoster (chicken pox and shingles) can also cause blisters that eventually crust. Pustular psoriasis causes pus-filled bumps but they do not contain bacteria.
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