What Really Works to Fight Skin Cancer

Get the latest on effective melanoma treatments.

1 / 5

If you or a loved one has been diagnosed with melanoma, either recently or in the past, one of your biggest questions is probably, "What are the latest and greatest treatments?"

The good news: In recent years, scientists have developed new therapies that are helping people fight this serious skin cancer and live longer.

Your treatment plan often depends on your cancer's stage and location. Options can range from minor surgery for early cancers to targeted therapies and immunotherapies for more advanced cancer. 

Here's a quick review of treatment options you can discuss with your doctor.


2 / 5 Surgery

Removing melanoma with surgery is often the first step, and for people with early-stage melanoma, it may be the only treatment needed. This involves getting rid of the melanoma and a small amount of normal tissue around it. The procedure can usually be done in a doctor's office using local anesthesia.

Mohs surgery, in which the melanoma is removed layer by layer in thin slices, may be used in certain situations. Mohs is also done to remove basal cell carcinoma and squamous cell carcinoma, two other types of skin cancer.

After removing the melanoma, your doctor may recommend a sentinel lymph node biopsy. This checks if the cancer has spread to nearby lymph nodes. If the test is positive, the affected lymph nodes will likely be removed with surgery.

Targeted therapy

3 / 5 Targeted therapy

When melanoma has spread and can't be removed with surgery, targeted therapy may be the next step. Because of the way these drugs home in on genetic changes in melanoma cells, they differ from chemotherapy treatments, which attack any dividing cells, even healthy ones. But targeted therapies work only if your melanoma has certain genetic characteristics. You can be tested to see whether these medications may work for you.

Targeted therapy drugs come mostly in pill form, depending on what kind you take. Side effects may include rash, nausea and sun sensitivity, but your reaction will depend on your prescription.


4 / 5 Immunotherapy

This type of treatment—considered a form of biological therapy—uses medications that work with your immune system to help detect and attack cancer cells. Immunotherapy is used to address many types of cancer, and is administered through injections, infusions and creams, depending on which treatment you need. Experts believe that the future of therapy for advanced melanoma will likely combine targeted therapy and immunotherapy. 

Other treatments

5 / 5 Other treatments

Some people may also need chemotherapy or radiation therapy. Although chemotherapy can destroy cancer cells, it may not work as well as immunotherapy or targeted therapy for treating melanoma, so it's often recommended when other treatments don't work. 

Radiation uses high-energy waves, like X-rays, to destroy cancer cells. It's sometimes used if surgery is not a viable option for certain patients. It may also be given to treat melanoma that has returned after surgery or to help relieve symptoms in cases where melanoma has spread. 

If you've been diagnosed with melanoma, it's important to understand all of your treatment options. Be sure to work closely with your doctor to treat your melanoma and to help prevent or delay recurrence.

This slideshow was updated on July 16, 2018.

more from this guide

Different Skin Cancer Spots and What They Mean Different Skin Cancer Spots and What They Mean

The statistics on skin cancer are scary: One in five Americans will develop it, and one person dies of skin cancer—usually melanoma, a rare but ...

Read More
How to Keep Melanoma From Coming Back
9 Sunscreen Mistakes You Don't Have to Make
Melanoma Diagnosis More Deadly for Men than Women Melanoma Diagnosis More Deadly for Men than Women