Are anesthetic sprays available to treat premature ejaculation?

Ian Kerner, PhD
Sexual Health
Researchers have developed an anesthetic spray that may have real benefits for premature ejaculation (PE).

The spray, called PSD502 or TEMPE (Topical Eutectic Mixture for Premature Ejaculation), contains an aerosol version of lidocaine and prilocaine, two numbing compounds. When sprayed on the penis, these compounds appear to increase intravaginal ejaculatory latency time (IELT): A study published on April 23, 2009, in the journal BJU International found that men with PE who used TEMPE spray 5 minutes before intercourse improved IELT from an average of about 15 seconds to about 3 minutes. Other research has shown similar findings and suggests that the spray significantly improves ejaculatory control and sexual satisfaction, with minimal side effects (mainly mild skin irritation). TEMPE spray is currently not available in the United States, although its manufacturer plans to submit it for U.S. Food and Drug Administration approval.

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