What should my child avoid while he is taking Kalydeco?

If your child is taking Kalydeco (ivacaftor), a prescription drug to treat a certain form of cystic fibrosis, he or she may need to avoid certain other medications, supplements and foods. The only foods to avoid are grapefruit or grapefruit juice and Seville oranges because they affect how the body metabolizes Kalydeco.

Many medications interact with Kalydeco, including some antibiotics, antiseizure drugs and supplements such as St. John's wort. Kalydeco may also make your child drowsy, so be careful about letting her play in possibly dangerous ways, such as bicycling, rollerblading or climbing jungle gyms. This is especially true when your child is first being treated with Kalydeco. Once you see how the drug affects your child, use your judgment.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.