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What should I avoid while taking Kalydeco?

While taking Kalydeco (ivacaftor), a drug to treat cystic fibrosis, you should avoid driving, operating machinery or doing anything else that requires you to be alert. That's because Kalydeco can cause drowsiness. Once you understand how the drug affects you, you may be able to do these things, but not at first. You should also avoid eating grapefruit or Seville oranges, or drinking grapefruit juice, as these can affect how your body metabolizes this drug. You should also avoid getting pregnant or breastfeeding, since it's unknown whether this drug may harm a developing fetus or may pass into breast milk.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.