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How are prescription and over-the-counter dimenhydrinate different?

Dimenhydrinate is an antihistamine and anticholinergic that is available as chewable tablets, oral solution, tablets, and solution for injection. When administered as a solution for injection, Dimenhydrinate is a prescription only medication used to treat motion sickness or vertigo. When administered in tablet, chewable tablet, or oral solution form it is available over-the-counter. When taken in tablet or chewable tablet form, Dimenhydrinate is also known as Dramamine, Driminate, Leader Motion Sickness Tablets, TripTone, and Wal-Dram and is used to treat motion sickness symptoms only, not vertigo. These tablets may be original formula or a less drowsy formula. Read the labels carefully as some forms of less drowsy Dramamine and generic tablets actually contain the active ingredient Meclizine, not Dimenhydrinate.  When treating motion sickness, Dimenhydrinate should be taken at least a half hour before travel or activity. 

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