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What is pulmonary Langerhans' cell histiocytosis (PLCH)?

Dr. Jeanne Morrison, PhD
Family Practitioner
Pulmonary Langerhans' cell histiocytosis (PLCH) is a rare and serious lung disease that occurs in adults. People with PLCH experience breathing impairment that may range from mild to severe. PLCH affects adults of all backgrounds, but the disease almost exclusively occurs in cigarette smokers. It is thought to be an abnormal inflammatory response of lung and immune cells to the toxins found in cigarette smoke. It is also referred to as pulmonary histiocytosis X, eosinophilic granuloma of the lung, and pulmonary Langerhans cell granulomatosis.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.