How does pulmonary Langerhans' cell histiocytosis (PLCH) affect the body?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner

Pulmonary Langerhans' cell histiocytosis (PLCH) primarily affects the lungs. Researchers aren't sure what causes it, but PLCH develops when the cells in the airways and tiny blood vessels in the lungs become swollen. This leads to damage of lung tissue. Partial and complete collapse of lung segments may occur in people with PLCH. Respiratory function of the lungs may be impaired, and breathing and oxygenation of the blood may be abnormal. In some cases, though, there are no noticeable symptoms, and the damaged tissue is only noticed through x-rays.

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