Your doctor should be able to confirm a case of generalized pustular psoriasis by a simple examination. It is important for your doctor to know where the pustules have appeared and to see what the pustules and surrounding skin look like. Knowing this will help determine if you have the generalized form, which affects wide areas of the body. The localized form can affect either your hands and feet (palmoplantar pustulosis) or the tips of your fingers and toes (acrodermatitis), and produces pustules about the size of a pencil eraser. A biopsy might be taken to confirm the diagnosis, but it is generally considered unnecessary.
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