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What is the role of the HPC1 gene in prostate cancer?

The genetic defects involved in the development of prostate cancer are only beginning to be understood, but research is progressing rapidly. One gene, the RNASEL gene, may have a mutation—HPC1—that is thought to cause one-third of all inherited cases of prostate cancer. Up to 10 percent of all cases of prostate cancer appear to have a genetic link. HPC1 appears to be especially common among African American men and may explain their high incidence rates. Researchers believe that the discovery of this gene will eventually lead to a simple blood test that could alert men of a possible increased risk.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.