How does Megace ES interact with other medications or food?

Megace ES has a few potential drug interactions. Combining Megace ES and dofetilide may increase the risk of serious heart problems, including irregular heart rhythms. Megace ES should not be taken by those using dofetilide. If rifampin and Megace ES are combined, the effectiveness of Megace ES may be reduced. If indinavir and Megace ES are combined, the effectiveness of indinavir may be deceased. Women should avoid hormonal birth control pills while taking this drug.

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