Who should not take Endometrin?

You should not take Endometrin (progesterone) if you have or think you have breast cancer. Endometrin should not be used by people who have bleeding or blood clotting problems. These may include blood clots in the lungs, eyes, and legs, or bleeding in the brain. Do not use this medication if you have unusual vaginal bleeding or have ever had a heart attack, liver disease, or stroke. Women who have recently had an abortion, miscarriage, or an ectopic pregnancy need to avoid Endometrin. Also, do not use Endometrin if you are using other vaginal medications, including vaginal antifungal cream. This drug is not approved for use in children. Taking Endometrin can worsen depression.