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What should I avoid while taking Zelboraf?

If you're taking the melanoma drug Zelboraf (vemurafenib), you may need to avoid certain medications or be closely monitored while taking them. These drugs include:  
  • antifungals such as itraconazole (Sporanox), ketoconazole (Nizoral) and voriconazole (Vfend)
  • antibiotics such as clarithromycin (Biaxin, in PrevPac), rifampin (Rifadin, in Rifamate, Rifater and Rimactane), rifapentine (Priftin) and telithromycin (Ketek)
  • HIV/AIDS drugs such as atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), saquinavir (Invirase) and rifabutin (Mycobutin)
  • heart medications such as amiodarone (Cordarone) and warfarin (Coumadin, Jantoven)
  • seizure medications such as carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal) and phenytoin
If you're a woman taking Zelboraf, you shouldn't get pregnant while taking Zelboraf; if you're a man being treated with the drug, you shouldn't get your partner pregnant. Hold off on trying to conceive until at least two months after you stop taking Zelboraf. Don't breastfeed while on this medication.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.