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What is pseudoephedrine hydrochloride and terfenadine?

Pseudoephedrine hydrochloride and terfenadine is a combination of two medications that treats hay fever and nasal congestion. Pseudoephedrine hydrochloride (HCl) is a decongestant that works by narrowing the blood vessels in the nasal passages. This reduces the inflammation caused by hay fever and colds, allowing you to breathe more easily. Terfenadine is an antihistamine. When your body is exposed to an allergen, your body responds by releasing histamines. Histamines attach to cells in your body, causing you to sneeze and your nose to run. Antihistamines like terfenadine prevent histamines from attaching to cells, relieving these symptoms. The combination of pseudoephedrine hydrochloride and terfenadine is known by the brand name Seldane-D. This drug was removed from U.S. markets in 1998 and is no longer available.

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