How does Xalkori work to treat lung cancer?

Stacy Wiegman, PharmD

Pharmacy

Xalkori (crizotinib) works by blocking proteins called kinases, which prevents the spread and growth of cancerous cells. The particular target of Xalkori is kinases produced by a specific gene called anaplastic lymphoma kinase (ALK); a mutation on that gene encourages cancer development. Your doctor will test to see if you have an ALK mutation. If you don't have it, Xalkori will not be prescribed.

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