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Can Zelboraf interact with other medications or foods?

Zelboraf (vemurafenib), a drug used to treat certain types of the melanoma, doesn’t interact with food. However, the drug can interact with many medications. Make sure your doctor and pharmacist has a complete list of all the prescription and nonprescription drugs, herbal remedies, and supplements that you take, especially:
  • antifungals such as itraconazole (Sporanox), ketoconazole (Nizoral) and voriconazole (Vfend)
  • antibiotics such as clarithromycin (Biaxin, in PrevPac), rifampin (Rifadin, in Rifamate, Rifater and Rimactane), rifapentine (Priftin) and telithromycin (Ketek)
  • HIV/AIDS drugs such as atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), saquinavir (Invirase) and rifabutin (Mycobutin)
  • heart medications such as amiodarone (Cordarone) and warfarin (Coumadin, Jantoven)
  • seizure medications such as carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal) and phenytoin (Dilantin, Phenytek)
  • antidepressant, such as nefazodone (Serzone)

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.