Can Prepopik interact with other medications or foods?

Prepopik (sodium picosulfate, magnesium oxide and citric acid), a pre-colonoscopy laxative, can interact with many other medications and certain foods. Do not eat solid foods or drink milk while taking Prepopik; you should drink only clear liquids.

Taking Prepopik with certain other medications can affect they work. Before you take Prepopik, let your doctor know about all your other medications (prescription and over-the-counter), as well as any supplements you take. In particular, tell your doctor if you take any of the following:
  • drugs for blood pressure or heart problems
  • drugs for kidney problems
  • drugs for seizures
  • water pills or diuretics
  • carbamazepine (Tegretol)
  • certain drugs for depression, anxiety and other mental problems
  • laxatives
  • tramadol (Ultram)
  • tetracycline
  • fluoroquinolone antibiotics
  • iron
  • digoxin (Lanoxin)
  • chlorpromazine
  • penicillamine (Cuprimine, Depen)
  • steroid drugs (such as prednisone or cortisone)
  • theophylline (Theochron) or aminophylline
  • nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.