Why isn't my generic drug working?

Remember, no drug -- brand or generic -- works exactly the same way for everyone. That's why I want you to be actively engaged in your own healthcare. If you are taking a drug that requires very precise control of the dose, a generic medication's "equivalent" status may not do the trick for you. This problem is common with thyroid medications. Even for less-demanding medical regimens, a generic drug might not work in the same way as a brand-name medication. Generic medication can use a slightly different "release" technology (altering how it gets into your system) and might have different inactive ingredients, such as binders, fillers, preservatives, coloring, and flavoring.