What effects do statins have on the aging process?

Mark C. Houston, MD
Internal Medicine
Statins are used to treat high cholesterol and reduce heart disease and stroke. They also have effects that are antioxidant, anti-inflammatory and anti-growth; they increase endothelial progenitor cells (stem cells for vascular function); and induce expression of telomere repeat binding factor, which protects telomeres (a part of our chromosomes) via a “capping” mechanism reducing senescence. They improve telomere life and thus extend life expectancy in animal models.

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