What is an exocrine tumor?

John A. Chabot on behalf of Columbia University Department of Surgery

Endocrinology Diabetes & Metabolism

Pancreatic cancer can result from a mutation in either the exocrine or endocrine function of the pancreas. Exocrine tumors are far more common, accounting for 95% of all cases. Adenocarcinoma is an exocrine tumor and is the most common kind of pancreatic cancer (80-90%).

Other rare forms of exocrine tumors include acinar cell carcinoma, adenosquamous carcinoma, and mucinous cystadenocarcinoma.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.

Pancreatic Cancer

Often asymptomatic in the beginning, pancreatic cancer is very difficult to diagnose and typically spreads rapidly to other parts of the body. Cancer occurs when abnormal cells form in the lining of the pancreas, an organ of the endocrine system that is responsible for making enzymes for digestion and for producing certain hormones such as insulin. Even though only 1 in 76 people develop this disease, it is the fourth deadliest type of cancer and is difficult to cure. No one knows what causes pancreatic cancer, and even the few known risk factors are not fully understood. Visit your doctor if you have unexplained weight loss, a loss of appetite, abdominal pain that radiates up your back, or a yellow tint to your eyes or skin.

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