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There are few proven, effective second-line treatments that are available to us. Any time that we can look at newer therapies that are available, or new combinations of therapies that are available, I think that is the appropriate route to take. If I’m talking about chemotherapy, then it has to be for an individual who's going to be able to tolerate the treatment. We have to make sure that the side effects of chemotherapy aren’t going to be too great to warrant the potential benefit of the treatment.
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