What medicines can treat complex regional pain syndrome type 1 (CRPS-1)?

Philip Getson
Pain Medicine

There are really 4 pains of CRPS and each should be treated accordingly:

  1. Muscle pain should be treated with muscle relaxants;
  2. Inflammatory (joint type) pain  should be treated with NSAIDS or short term steroids;
  3. Burning pain pathognomonic to CRPS is treated with anti-epileptics(Lyrica, gabapentin and others); and, 
  4. Deep pure pain  requires analgesics from the mildest (tramadol) to Class II opoid (Morphine, oxycodone, etc.).

Associated pains like headaches and abdominal pains require specific medications as well. One of the great mistakes in CRPS treatment is to treat "pain" - thinking the one drug will do it all, inevitably this leads to failure.


Continue Learning about Pain Conditions

What is the prognosis for arachnoiditis?
Riverside Center for NeurosciencesRiverside Center for Neurosciences
Arachnoiditis appears to be a disorder that causes chronic pain and neurological deficits and does n...
More Answers
What is an inflammatory effect?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
Your body doesn't just form allies or fight enemies based on how many calories a particular food has...
More Answers
When is neck or back pain a sign of a serious medical condition?
Gerald M. SilvermanGerald M. Silverman
On very rare occasions, neck or lower back pain can be a sign of a serious underlying medical co...
More Answers
When is surgery the best option for joint pain?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
When it comes to joint injuries, healing with steel is not the first choice. The major benefit of su...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.