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It is not known how interstitial cystitis affects overactive bladder. Interstitial cystitis is a rare disorder also known as “painful bladder syndrome.” It is a chronic inflammation of the bladder wall. The main symptoms are painful, frequent urination. Interstitial cystitis may occasionally cause urine to leak. Both interstitial cystitis and overactive bladder may include nocturia. This is frequent urination at night.
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