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What is the risk of malignancy index (RMI) for ovarian cancer?

David A. Fishman, MD
Gynecologic Oncology
Risk of malignancy index (RMI) is a tool currently being used in women who have no symptoms of ovarian cancer. It allows patients who are more likely to have epithelial ovarian cancer to be triaged into a group that would be seen by a gynecologic oncologist compared with patients with a lower probability of malignancy. Those patients would be managed by a practitioner without advanced training.

RMI is obtained by multiplying serum cancer antigen 125 (CA125) levels in U/mL, by a score given for specific pelvic ultrasound findings, and by a score given for menopausal status.

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