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Is ovarian cancer associated with any genetic diseases?

Hereditary nonpolyposis colorectal cancer (HPNCC), Peutz-Jeghers Syndrome, and Cowden's disease may be associated with ovarian cancer. MLH1, MLH2, and PMS1 are three genes which may be mutated in those with HPNCC. These genes allow cells to repair mistakes that occur in DNA during division. When they do not function properly, DNA mutations may occur, leading to abnormal cell growth and division, and ultimately, cancer.

Ovarian cancer is associated with BRCA1 and BRCA2 genetic mutations. Ovarian cancer is also associated with Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.