Advertisement

Is ovarian cancer associated with any genetic diseases?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner

Hereditary nonpolyposis colorectal cancer (HPNCC), Peutz-Jeghers Syndrome, and Cowden's disease may be associated with ovarian cancer. MLH1, MLH2, and PMS1 are three genes which may be mutated in those with HPNCC. These genes allow cells to repair mistakes that occur in DNA during division. When they do not function properly, DNA mutations may occur, leading to abnormal cell growth and division, and ultimately, cancer.

Ovarian cancer is associated with BRCA1 and BRCA2 genetic mutations. Ovarian cancer is also associated with Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer.

Continue Learning about Ovarian Cancer

6 Tips to Keep a Consistent Medication Routine
6 Tips to Keep a Consistent Medication Routine
Many people living with cancer struggle to take medications as directed, for a variety of reasons. Use the tips in this video to help keep a consisten...
Read More
What is the role of VCAM-1 in ovarian cancer?
David A. Fishman, MDDavid A. Fishman, MD
VCAM-1 is a receptor on the surface of activated endothelial and mesothelial cells. In instances...
More Answers
What should I ask my doctor once diagnosed with ovarian cancer?
Nimesh P. Nagarsheth, MDNimesh P. Nagarsheth, MD
Find out your doctor's qualifications for treating ovarian cancer, learn about your treatment plan a...
More Answers
What Symptoms of Ovarian Cancer Can Be Mistaken for Other Things?
What Symptoms of Ovarian Cancer Can Be Mistaken for Other Things?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.