How can contrast-enhanced sonography help diagnose ovarian cancer?

Contrast enhanced sonography may significantly improve the diagnostic ability of ultrasound to identify early microvascular changes that are known to be associated with early stage ovarian cancer. Currently, contrast agents play a pivotal role in the imaging modalities of computed tomography (CT) and magnetic resonance imaging (MRI) by increasing image conspicuity. By increasing the density or signal intensity of a particular organ and thus, the signal to noise ratio, contrast agents help to detect and characterize parenchymal lesions. Indeed, contrast agents have received such widespread acceptance that a CT exam performed without intravenous contrast for many indications is now considered limited.