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What genetic mutations cause ovarian cancer?

Mutations tumor suppressor genes BRCA1 or BRCA2 can predispose women to breast or ovarian cancer. Normally, these genes prevent cells from growing and dividing too quickly. If you have a mutation in either gene, your cells are less able to stop abnormal growth and the development of cancer. For every 100 women with BRCA2 mutations, between 10 and 30 will get ovarian cancer before 70 years of age. BRCA1 mutations carry a higher risk, and up to 70 percent of women who carry a mutation may get ovarian cancer.

 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.